Title: Spaces of Entire Functions in Spectral Problems Abstract: The Krein - de Branges theory of Hilbert spaces of entire functions was introduced around mid 20th century to treat spectral problems related to differential operators and canonical systems. Since then, the theory has become a fundamental part of spectral and complex analysis. It was applied in numerous important problems, e.g. Marchenko's proof of the uniqueness of the inverse spectral problem for Schroedinger operators. The course covers the basics of the theory, its connections with other branches of complex and harmonic analysis and recent applications.